Entropic Evolution

Thoughts of a Computational Biologist

Exchanging lysines for arginines with increases in GC content: correlations!

Note: No guaranties whatsoever. If you want to try the exercise, I have the original table of genomes with their sizes and GC content at figshare. Click here to download … Continue reading

May 14, 2013 · Leave a Comment

Exchanging lysines for arginines with increases in GC content: counts

Note: No guaranties whatsoever. If you want to try the exercise, I have the original table of genomes with their sizes and GC content at figshare. Click here to download … Continue reading

May 6, 2013 · Leave a Comment

Exchanging lysines for arginines with increases in GC content: choosing a genome subset

Note: No guaranties whatsoever. If you want to try the exercise, I have the original table of genomes with their sizes and GC content at figshare. Click here to download … Continue reading

May 3, 2013 · Leave a Comment

Exchanging lysines for arginines with increases in GC content: preparation

Note: No guaranties whatsoever. If you want to try the exercise, I have the original table of genomes with their sizes and GC content at figshare. Click here to download … Continue reading

April 26, 2013 · Leave a Comment

Compiling NCBI’s blast 2.2.28+ in Mountain Lion

Note: left gutter and numbers in shell commands below to help differentiate the terminal commands and outputs from the text describing what I did. Recently, NCBI sent an e-mail about … Continue reading

April 12, 2013 · Leave a Comment

Note on the perl programming example for newbies

Note: Not intended for professional programmers, but as example for non-programmers wishing to see some programming action. Also a disclaimer: No warranties whatsoever. In the little perl programming example for … Continue reading

March 27, 2013 · Leave a Comment

Little PERL programming example for biology newbies

Note: Not intended for professional programmers, but as example for non-programmers wishing to see some programming action. Also a disclaimer: No warranties whatsoever. During an exercise in my intro course … Continue reading

March 22, 2013 · 2 Comments

And now BLAT 35 won’t compile in my Mountain Lion, or will it?

I just learned that the new version of the BLAST-like alignment tool, blat 35, was released last november. So, of course, I immediately downloaded and tried to compile it. Followed … Continue reading

February 14, 2013 · Leave a Comment

If FTPing files from NCBI is too slow, they have rsync!

A quick tip. NCBI’s genomic files are not compressed, which translates into slow file transfer. However, the server can also be accessed via rsync, and the “-z” option in rsync … Continue reading

February 2, 2013 · Leave a Comment

If ssearch36 gets stuck while comparing sequences in your mac

Quick note. When I was comparing the protein sequences from C. glomerans PW2 to those in E. coli K12 MG1655, the program would get stuck with this sequence: >gi|328954742|ref|YP_004372075.1| MSKTIPELTLDNFDLVMQSKLPVLVDFWAPWCGPCRTLSPIVEQVAEEMSERITVAKCNVDENQDLAMKYGVMS IPTLVLFRDGAEVSRTVGAMPKPKLVAEIEKNL … Continue reading

January 25, 2013 · Leave a Comment
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